Direct Cell Lineage Conversion: A Potential Approach for Replacing Damaged Heart Muscles
The underlying pathology of ischaemic heart disease in adults is typically damage to and the loss of cardiomyocytes (heart muscle cells) that leads to heart failure (1). After embryonic development, cardiomyocytes have little to no capacity to regenerate (1). This is a fundamental issue in treating heart disease. Because much of heart disease is the [...]